HPS0760-95
120066-38-8
默认>95%HPLC,若需其他规格请洽询
产品编号 | 规格 | 货期 | 销售价 | 折扣价 | 数量 | 操作 |
---|---|---|---|---|---|---|
HPS0760-95 | 默认>95%HPLC,若需其他规格请洽询 |
25天
|
敬请询价 | 敬请询价 |
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名字 | CRF (6-33) (human, rat) |
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序列(三字母) | H-Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Gln-Ala-His-Ser-OH |
序列(单字母) | ISLDLTFHLLREVLEMARAEQLAQQAHS |
CAS# | 120066-38-8 |
分子式 | C₁₄₁H₂₃₁N₄₁O₄₃S |
分子量 | 3220.7 |
纯度 | 默认>95%HPLC,若需其他规格请洽询 |
合成方法 | Synthetic |
储存条件 | -20 ± 5 °C |
应用 | Alzheimer´s Disease |
描述 | This CRF fragment may have two different beneficial effects in Alzheimer´s disease (AD). First CRF (6-33) dissociates CRF from the CRF-binding protein and may therefore be able to restore the dramatic reduction of free CRF content in AD. Second this fragment shows cognition-enhancing properties in animal models of learning and memory, without the characteristic anxiogenic effects of CRF receptor agonists, and may therefore be useful in the treatment of memory deficits seen in AD. |